Gebze
İlhan Tarkun
Prof.

İlhan Tarkun

Joined the Anadolu Medical Center in 2018 in the position of endocrinology specialist.

Speciality

  • Endocrinology and metabolic diseases
  • Diabetes Thyroid diseases
  • Hypophysis diseases Obesity
  • Diseases of the adrenal gland

Education

  • 1989 – Marmara University, Faculty of Medicine
  • 1996 – Specialisation in internal diseases at the Hospital for Diagnostics and Analytics Haydarpaşa Istanbul 
  • 2001 – Further specialisation at the Kocaeli University, Faculty of Medicine, Division of Internal Diseases, Department of Endocrinology and Metabolic Disorders 
  • 2006 – Assistant professor at the Kocaeli University, Faculty of Medicine, Division of Internal Diseases, Department of Endocrinology and Metabolic Disorders
  • 2011 – 2018 Professor at the Kocaeli University, Faculty of Medicine, Division of Internal Diseases, Department of Endocrinology and Metabolic Disorders

Institutions Worked At

Graduated from Marmara University, Faculty of Medicine, in 1989, and completed his specialist education in internal diseases at the Hospital for Diagnostics and Analytics Haydarpaşa Istanbul. Took up a position at Kocaeli University in 1999 to further specialise in endocrinology and metabolic disorders. Completed his specialist education in endocrinology and metabolic diseases in 2001, became assistant professor in 2006 and was later appointed professor at the same university. Worked in the university’s Department of Endocrinology and Metabolic Disorders from 2011-2018. Joined the Anadolu Medical Center in 2018 in the position of endocrinology specialist. 

“Lipoprotein (a) concentrations in patient with type 2 diabetes mellitus without cardiovascular diseaserelationship to metabolic parameters and diabetic complications”, Türkiye Diyabet Vakfı, Diabetes Mellitus Bilimsel Yayın Destek Ödülü, En İyi Makale Üçüncülük Ödülü (2003).

“Bozulmuş glukoz toleransı veya açlık glukozu bulunan 102 hastanın yaklaşık iki yıllık izlem sonuçları”, II. Türk Obezite Kongresi ve I. Beslenme Sempozyumu, 2004, Denizli, Mansiyon Ödülü.

“Endothelial dysfunction in young woemn with polycystic ovary syndrome:Relationship with insulin resistance and lowgrade chronic inflammation”, Türkiye Diyabet Vakfı, Diabetes Mellitus Bilimsel Yayın Destek Ödülü, En İyi Makale Birincilik Ödülü (2005).

53. Ulusal Diyabet Kongresi, En İyi Bildiri Üçüncülük Ödülü (2017).

  • Member of the board of directors of the Turkish Diabetes Association 
  • Member of the board of trustees of the Turkish Diabetes Foundation 
  • Member of the Accreditation and Competency Board of the Turkish Endocrinology and Metabolic Diseases Society
  • Turkish Endocrinology and Metabolic Diseases Society
  • American Diabetes Association (ADA)
  • American Diabetes Organisation (ENDO)

Awards

2003 - Third prize in the Best Publication category of the Scientific Publication Support Award on Diabetes Mellitus of the Turkish Diabetes Foundation for a study entitled: “Lipoprotein (a) concentrations in patient with type 2 diabetes mellitus without cardiovascular disease relationship to metabolic parameters and diabetic complications”.


2004 – Honourable mention at the 1st Nutrition Symposium and 2nd Turkish Obesity Congress, Denizli, for his study on “Bozulmuş glukoz toleransı veya açlık glukozu bulunan 102 hastanın yaklaşık iki yıllık izlem sonuçları – Results of about two years of observation of 102 patients with glucose tolerance disorder or fasting glucose”


2005 – First prize in the Best Publication category of the Scientific Publication Support Award on Diabetes Mellitus of the Turkish Diabetes Foundation for a study entitled: “Endothelial dysfunction in young women with polycystic ovary syndrome: Relationship with insulin resistance and low grade chronic inflammation”, 


2017 – Third prize in the Best Presentation category at the 53rd National Diabetes Congress

1. Selek A., Çetinarslan B., Cantürk Z., Tarkun İ., Akyay OZ., Çabuk B., Ceylan S., The Utility of Preoperative ACTH/Cortisol Ratio for the Diagnosis and Prognosis of Cushing's Disease, J. Neurosci Rural Pract. 2018 Jan-Mar; 9(1): 106-11. doi: 0.4103/jnrp.jnrp_308_17.
 

2. Gürkan E., Tarkun İ.*, Şahin T., Effect of Exenatide on Aortic Stiffness and Blood Pressure Parameters. Turkish Journal of Endoc. Metab. 2017 21(4); 97-103.


3. İ. Tarkun, S. Dumanlı Attitudes, wishes, and needs of diabetes patients and their relatives: Turkish data from the DAWN2 study. Turkish J. Med Sci 2017 Apr 18;47(2):447-45.

4. Karci AC, Canturk Z, Tarkun İ., Çetinarslan B.,  Matrix metalloproteinase 2 (MMP-2) levels are increased in active acromegaly patients.

5. Selek A, Çetinarslan B, Tarkun İ, Cantürk Z, Üstüner B, Akyay Z.,  Thyroid autoimmunity: is really associated with papillary thyroid carcinoma? Eur Arch Otorhinolaryngol. 2017 Mar; 274(3): 1677-1681.

6. Selek A., Barış S., Çetinarslan B., Cantürk Z., Tarkun İ., Akyay Z., New-Onset Sarcoidosis After Remission of Cushing's Syndrome. Turk Thorac J. 2016 Jan;17(1):35-37.

7. Selek A., Çetinarslan B., Kıvrakoğlu E., Karadağ DT., Tarkun İ., Cantürk Z., Akyay OZ., Histologic outcome of thyroid nodules with repeated diagnosis of atypia in thyroid fine-needle aspiration biopsy. Future Oncol. 2016 Mar; 12(6): 801-5.

8. Selek A., Çetinarslan B., Gürbüz Y., Tarkun İ., Cantürk Z., Çabuk B. Aromatase enzyme expression in acromegaly and its possible relationship with disease prognosis. Endocrine 2015 May; 49(1):250-7.

9. Green JB, Bethel MA, Armstrong PW, Buse JB, Engel SS, Garg J., Josse R., Kaufman KD, Koglin J., Korn S., Lachin JM, McGuire DK, Pencina MJ, Standl E, Stein PP, Suryawanshi S., Van de Werf F., Peterson ED, Holman RR; TECOS Study Group. Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes. N. Engl J. Med. 2015 Jul 16;373(3):232-42.
 

10. Gürkan E., Tarkun İ., Şahin T., Çetinarslan B., Cantürk Z., Evaluation of exenatide versus insulin glargine for the impact on endothelial functions and cardiovascular risk markers. Diabetes Res Clin Pract. 2014 Dec;106(3): 567-75.


11. Gürkan E., Gürbüz Y., Tarkun İ., Cantürk Z., Çetinarslan B. Mixed medullary-papillary carcinoma of the thyroid: report of two cases and review of the literature. Indian J. Pathol Microbiol. 2014 Oct-Dec;57(4):598-602

12. Komşuoglu Çelikyurt I., Mutlu O., Ulak G., Uyar E., Bektaş E., Yıldız Akar F., Erden F., Tarkun İ., Exenatide treatment exerts anxiolytic- and antidepressant-like effects and reverses neuropathy in a mouse model of type-2 diabetes. Med Sci Monit Basic Res. 2014 Jul 30; 20: 112-7. 

13. Nicolucci A., Kovacs Burns K., Holt RI., Comaschi M., Hermanns N., Ishii H., Kokoszka  A., Pouwer F., Skovlund SE., Stuckey H., Tarkun İ., Vallis M., Wens J., Peyrot M Diabetes Attitudes, Wishes and Needs second study (DAWN2™): cross-national benchmarking of diabetes-related psychosocial outcomes for people with diabetes. DAWN2 Study Group. Diabet Med. 2013 Jul; 30(7): 767-77.

14. Holt RI, Nicolucci A., Kovacs Burns K., Escalante M., Forbes A., Hermanns N, Kalra S., Massi-Benedetti M., Mayorov A., Menéndez-Torre E., Munro N., Skovlund SE.,  Tarkun İ., Wens J., Peyrot M. Diabetes Attitudes, Wishes and Needs second study (DAWN2™): cross-national comparisons on barriers and resources for optimal care-healthcare professional perspective.;. Diabet Med. 2013 Jul; 30(7): 789-98. 

15. Kovacs Burns K., Nicolucci A, Holt RI., Willaing I, Hermanns N., Kalra S., Wens J., Pouwer F., Skovlund SE, Peyrot M.; DAWN2 Study Group Diabetes Attitudes, Wishes and Needs second study (DAWN2™): cross-national benchmarking indicators for family members living with people with diabetes. Diabet Med. 2013 Jul; 30(7): 778-88. 

16. Emre Dikmen, İlhan Tarkun, Zeynep Cantürk, Berrin Çetinarslan, Plasma visfatin level in women with polycystic ovary syndrome. Gynecological Endocrinology 27(7): 475-479, 2011.

17. Emre Dikmen, İlhan Tarkun, Funda Öztürk, Berrin Arslan, Zeynep Cantürk. Plasma adiponectin and resistin levels in women with polycystic ovary syndrome: relation to body mass index and insulin resistance. Turkish Journal of Medical Sciences 41(1): 45-52, 2011.

18. Erdem Türemen, Berrin Çetinarslan, Tayfun Şahin, Zeynep Cantürk, İlhan Tarkun. Endothelial dysfunction and low grade chronic inflammation in subclinical hypothyroidism due to autoimmune thyroiditis. Endocrine Journal 58(5): 349-354, 2011.

19. Tarkun İ, Dikmen E,, Cetinarslan B,, Cantürk Z., Impact of treatment with metformin on adipokines in patients with polycystic ovary syndrome. European Cytokine Network 21(4); 272-77.

20. Türemen E., Arslan B., Tarkun İ., Cantürk Z., “Cushingoid stria and Cushingoid appearance in a patient with incidentaloma.” Endocrine Practice, 12 (1):103-104 (2006) .

21. Tarkun İ., Çetinarslan B., Türemen E., Şahin T., Cantürk Z., “Effect of Rosiglitazone on insulin resistance, C-reactive protein and endothelial function in nonobese young women with PCOS” European Journal of Endocrinology, 153, 115-121 (2005). 

22. Tarkun İ., Hacıhanefioğlu A., Tarkun P., Çetinarslan B., Cantürk Z. “Anticardiolipin and anti-β2 glycoprotein I antibody concentrations in patients with type 2 diabetes mellitus”, Diabetes Research and Clinical Practice, 68, 181-187 (2005).

23. Özdemir G, Özden M, Maral H, Kuskay S, Çetinalp P, Tarkun İ. “Malondialdehyde, glutathione, glutathione peroxidase and homocysteine levels in type 2 diabetic patients with and without microalbuminuria.” Annals of Clinical Biochemistry  42, 99-104 (2005).

24. Tarkun İ., Arslan B., Cantürk Z., Türemen E., Şahin T., Duman C. “Endothelial dysfunction in young women with polycystic ovary syndrome: Relationship with insulin resistance and low-grade chronic inflammation”, Journal of Clinical Endocrinology and Metabolism, 89, 5592-5596 (2004) ( Bu yayının özeti aşağıdaki dergi tarafından JCEM’ den izin alınarak ve editör yorumu eklenerek Obstetrical and Gynecological Survey  60, 180-181, 2005 yayınlanmıştır). 

25. Tarkun İ., Cantürk Z., Arslan B., Türemen E., Tarkun P. “The plasminogen activator system in young and lean women with polycystic ovary syndrome”, Endocrine Journal, 51, 467-472 (2004).

26. Şengül E., Çetinarslan B., Tarkun İ., Cantürk B., Türemen E. “Homocysteine concentrations in subclinical hypothyroidism”, Endocrine Research, 30, 351-359 (2004).

27. Tarkun İ., Çetinarslan B., Cantürk Z., Tarkun P., Ağaçdiken A., Komşuoğlu B. “Homocysteine concentrations in type 2 diabetic patients with silent myocardial ischemia: A predictive marker”, Journal of Diabetes and its Complications, 18, 165-168 (2004).

28. Cantürk Z., Çetinarslan B., Tarkun İ., Cantürk N.Z., Özden M. “Lipid profile and lipoprotein (a) as a risk factor for cardiovascular disease in women with subclinical hypothyrodism”, Endocrine Research, 29, 307-16 (2003).

29. Cantürk Z., Çetinarslan B., Tarkun İ., Cantürk N.Z. “Serum ferritin levels in poorly and well controlled diabetes mellitus”, Endocrine Research, 29, 299-306 (2003).

30. Cantürk Z., Çetinarslan B., Tarkun İ., Cantürk N.Z., Özden M., Duman C. “Hemostatic system as a risk factor for cardiovascular disease in women with subclinical hypothyroidism”, Thyroid ,13, 971-7 (2003).

31. Cantürk Z., Cantürk N.Z., Çetinarslan B., Utkan N.Z., Tarkun İ., “Nosocomial infections and obesity in surgical patients”, Obesity Research, 11, 760-75 (2003). 

32. Çetinarslan B., Akkoyun M., Cantürk Z., Tarkun İ., Kahraman G., Komsuoğlu B. “Duration of the P wave dispersion in subclinical hyperthyroidism”, Endocrine Practice, 9, 200-203 (2003).

33. Tarkun İ., Çetinarslan B., Cantürk Z. “Lipoprotein (a) concentrations in patients with type 2 diabetes mellitus without cardiovascular disease: relationship to metabolic parameters and diabetic complications”, Nutrition Metabolism and Cardiovascular Disease, 12, 127-131 (2002).
 

Over 150 oral and poster presentations at national and international congresses

As of 2018, his publications have been cited over 1200 times.

Areas of Interest

What Is Dopamine? What Does Dopamine Do?

Dopamine is a type of neurotransmitter synthesized in the hypothalamus region of the brain. Neurotransmitters, which can be described as the chemical messengers of the body, carry messages from any nerve cell in the body to the next nerve, muscle, or gland cell. This process enables the movement of limbs, activates the sense of feeling, maintains heartbeats, and allows the body to respond to any information received from the environment.

What is Growth Hormone and What are the Symptoms of its Deficiency?

Growth hormone is a hormone that plays a significant role in the development and growth of the body. Secreted by the pituitary gland, this hormone supports the growth of bones during childhood, increases muscle mass, and promotes overall body development. Therefore, a deficiency in growth hormone can affect these important processes. This deficiency can lead to short stature in children and a decrease in energy levels and muscle mass in adults.

Thyroid Disease and Treatment

The thyroid gland is a butterfly-shaped organ located at the front of the neck. It is responsible for secreting thyroid hormones, which play crucial roles in metabolism. An underactive or overactive thyroid can lead to significant health problems.

What is Klinefelter Syndrome?

Klinefelter syndrome (KS) is a chromosomal disorder that is one of the primary causes of infertility in men. Also known as 47, XXY syndrome, many cases of Klinefelter syndrome may present no symptoms, which is why men who experience difficulties conceiving naturally may need to be evaluated for 47, XXY syndrome. Answers to questions like "What is Klinefelter syndrome, what are its symptoms, and how is it treated?" and detailed information on this topic are covered in the following sections.

TSH: What It Is, Its Test, High and Low Levels

The TSH test is a diagnostic tool that shows how well the thyroid glands are functioning. Detecting whether the thyroid glands are underactive or overactive is crucial for determining the appropriate treatment for the patient. This test can be performed for individuals already diagnosed with thyroid disease for monitoring purposes or as a screening tool to detect thyroid disorders in otherwise healthy individuals.

Thyroid: What is it, Symptoms, Diagnosis, and Treatment

The thyroid gland is a vital hormone gland that plays an important role in the body's metabolism, growth, and development. A steady amount of thyroid hormone is constantly present in the bloodstream, helping to regulate many body functions. During specific conditions such as growth, development, or pregnancy, the body requires more energy. In such cases, the thyroid gland produces more hormones. The thyroid gland is located at the front of the neck, below the vocal cords, and is butterfly-shaped. The thyroid gland weighs between 20 and 60 grams on average and is surrounded by two fibrous capsules. The outer capsule is connected to the laryngeal muscles and many important vessels and nerves. There is loose connective tissue between the inner and outer capsules. Therefore, the thyroid can move and change its position during swallowing. The thyroid tissue itself consists of numerous small individual lobules surrounded by thin connective tissue layers. These lobules contain many small vesicles called follicles, which store thyroid hormones in small droplets. The thyroid gland produces three hormones. These hormones are: Triiodothyronine, also known as T3 T4 Calcitonin Calcitonin, produced by C cells in the body, is involved in calcium and bone metabolism. T3 and T4 hormones increase the basal metabolic rate, making all cells in the body work harder.

What is Type 2 Diabetes? What Are Its Symptoms?

Diabetes, also known as "sugar disease" in the public, is one of the most important public health issues today. According to the International Diabetes Federation, 1 in every 11 people worldwide between the ages of 20 and 79 has diabetes, and this number is expected to rise to 1 in 10 by 2045. With many undiagnosed cases, diabetes affects the organs and vital functions of patients, reducing their quality of life. While there are some rare types of diabetes, it is typically categorized into two types in the community. Type 1 diabetes, often referred to as Juvenile Type, occurs primarily in children and young people. In Type 1 diabetes, there is a dysfunction in the insulin production by the beta cells in the pancreas. Type 2 diabetes is the most common form of diabetes in the population. In Type 2 diabetes, insulin is produced, but there is a problem with its cellular utilization.

Gynecomastia: What It Is, Causes, Symptoms, and Treatment

Gynecomastia is derived from the Greek words "gyne" (woman) and "mastia" (breast), meaning having breasts like a woman.

Insulin Resistance: What It Is, Symptoms, Diagnosis & Treatment

What is Insulin Resistance? Insulin resistance refers to a condition where biological processes that should normally occur in response to insulin hormone levels, which may be normal or elevated, do not take place properly. The liver, muscle tissue, and adipose tissue are the primary organs affected by insulin. As insulin resistance develops, the pancreas may produce more insulin in an attempt to overcome the resistance. This leads to a condition known as hyperinsulinemia, where insulin levels in the blood are significantly higher than normal. Over time, insulin resistance can progress to metabolic syndrome or type 2 diabetes (diabetes mellitus) and other clinical conditions. It is estimated that approximately 9% of the global population is affected by type 2 diabetes, which can develop as a result of insulin resistance. Other conditions related to insulin resistance include obesity, cardiovascular diseases (heart and blood vessel diseases), non-alcoholic fatty liver disease, metabolic syndrome, and polycystic ovary syndrome (PCOS).

Hypoglycemia: What It Is, Its Causes, Symptoms, and Treatment

Low blood sugar (hypoglycemia) is a dangerous and important health condition that requires attention. People whose blood sugar drops excessively are often those with diabetes. The cause of this condition is related to the medications used in diabetes treatment, which either contain insulin directly or increase the effectiveness of the hormone.

Hyperthyroidism: What It Is, Symptoms, Causes, and How to Treat It

Hyperthyroidism is a condition in which the thyroid gland produces too much thyroid hormone. As a result, your body's metabolism may speed up, leading to unintentional weight loss and rapid or irregular heartbeats, among other symptoms. There are various treatments available for hyperthyroidism. Anti-thyroid medications that slow down the production of thyroid hormones and radioactive iodine may be used. Sometimes, as part of the treatment, the entire thyroid gland or a portion of it may be surgically removed.

Hashimoto: What It Is, Causes, Symptoms, and Treatment

Hashimoto's disease is a condition that affects the thyroid gland. This disease, also known as Hashimoto's thyroiditis, causes the thyroid gland to become underactive.

Hidden Sugar: What It Is, Symptoms, Diagnosis, and Treatment

Hidden sugar is a condition that closely affects the circulation, nerves, and immune system. This is because, if left untreated, it can manifest as Type 2 diabetes. It is often overlooked, especially in children and adults, since it doesn't present symptoms in the early stages. However, with regular doctor check-ups, it can be diagnosed and treated before it turns into Type 2 diabetes. Additionally, people with a family history of diabetes should take preventive steps to manage hidden sugar, as it is important for their health.

What is Diabetes? What are the Symptoms of Diabetes?

Most people know diabetes as "sugar disease." However, this is only one aspect of it. Simply put, diabetes, known as diabetes mellitus, is a chronic disease characterized by high levels of glucose (sugar) in the bloodstream.

Night Sweats

Individuals experiencing night sweats may find that their sheets or pajamas are soaked with water upon waking. Regulating the sleeping environment through various methods is the first step that can be taken to address this issue. In cases where night sweats occur due to an underlying medical condition, it is essential to consult healthcare providers for the identification of the underlying disorder and to consider appropriate treatment options. This condition, referred to as sleep hyperhidrosis, usually arises from manageable diseases, but it can also occur as a sign of life-threatening conditions, making it beneficial to be informed. You can follow the continuation of this article for more information on other topics related to night sweats.