Gebze
Mehmet Çağlar Berk
Prof.

Mehmet Çağlar Berk

He has been working as neurosurgery specialist in Anadolu Medical Center since 2023.

Speciality

  • Brain and spine tumors
  • Image-guided neurosurgery
  • Minimally invasive brain and spine surgery
  • Stereotactic and functional neurosurgery
  • Surgical treatment of movement disorders and epilepsy
  • Pediatric neurosurgery

Education

Medical Education: 
Hacettepe University Faculty of Medicine, Ankara, Turkey 10/1983-07/1989  

Neurosurgical Training: 
Resident                            
Department of Neurological Surgery 
Oregon Health and Science University
Portland, OR, USA
07/2006-06/2012

Clinical Fellow in Pediatric Neurosurgery
St. Louis Children’s Hospital, Department of Neurosurgery
Washington University School of Medicine in St. Louis St. Louis, MO, USA
07/2005-06/2006 

Clinical Fellow in Pediatric Neurosurgery
Division of Neurosurgery, University of Ottawa
Children’s Hospital of Eastern Ontario,
Ottawa, Ontario, Canada
07/2004-10/2004   

Postdoctoral Research Fellow
Department of Neurosurgery,
Louisiana State University Health Sciences Center in Shreveport,
Shreveport, LA, USA
08/2003-04/2004

Clinical Fellow in Stereotactic and Functional Neurosurgery
Division of Neurosurgery, Dalhousie University,
Queen Elizabeth II Health Sciences Centre,
Halifax, Nova Scotia, Canada
07/2002-06/2003

Clinical Fellow in Stereotactic and Functional Neurosurgery
Surgical Center for Movement Disorders,
Division of Neurosurgery, University of British Columbia,
Vancouver, British Columbia, Canada
07/2000-06/2002

Resident, Department of Neurosurgery,
Ankara University School of Medicine, Ankara, Turkey
07/1992-07/1998

Institutions Worked At

  • Oregon Health and Science University
  • Washington University in St. Louis
  • Louisiana State University
  • Dalhousie University
  • University of Ottawa
  • University of British Columbia
  • KOSTÜ Kocaeli University of Health and Technology Faculty of Health Sciences Faculty Member
  • KOSTÜ Kocaeli University of Health and Technology Faculty of Pharmacy Acting Dean
  • Board Certified by the American Board of Neurological Surgery: ABNS Certificate #191137188
  • 11/2019-12/2029, Participating in MOC
  • ECFMG/USMLE Certification: 2005
  • Licentiate of Medical Council of Canada - LMCC: 2005
  • Graduate Certificate in Human Investigations
  • Oregon Health and Science University, Portland, OR, USA:  2011
  • FEBNS - Fellow of European Board of Neurosurgery: 1998
  • Republic of Turkiye, Ministry of Health, 
  • Specialty certificate in Neurosurgery: 1998
  • TND - Turkish Board of Neurosurgery: 2006

1- History of immunology.

Berk MC

Bulletin of Physiology, Hacettepe University School of Medicine

1991, 3:68-74 (Turkish)

 

2- Pediatric intraspinal tumors.

Dincer C, Berk C, Baskaya MK, Gokalp HZ, Arasil E

Turkish Journal of Spinal Surgery 1993, 4:68-74

 

3- Ampicillin-sulbactam combination prophyaxis in rhinorhea.

Berk C, Çaglar S, Selçuki M, Arasil E

Turkish Journal of Chemotheraphy 1994, 8:124 (Turkish)

 

4- Management of myelomeningocele.

Dincer C, Unlu A, Berk C, Temiz C

Turkish Journal of Neurosurgery 1993, 6:59 (Turkish)

 

5- The causes and prevention of failed back surgery syndrome.

Egemen N, Çaglar S, Berk C

Turkish Journal of Neurosurgery 1994, 7:43 (Turkish)

 

6- Giant cholesterol cyst of the petrous bone: a case report. 

Gökalp HZ, Deda H, Baskaya MK, Berk MC

Neurosurg Rev 1995, 18:205-208

 

7- The Webino syndome: a case report.

Selçuki D, Temiz C, Akarsan Y, Yücemen N, Berk C

Journal of Cerebrovascular Disorders 1995, 1:36 (Turkish)

 

8- Treatment of CSF fistulae.

Berk C, Çaglar S, Selçuki M, Deda H, Arasil E, Avci E

Turkish Journal of Neurosurgery 1995, 8:37 (Turkish)

 

9- Surgical treatment alternatives for craniofacial pain.

Kanpolat Y, Savas A, Çaglar S, Aydin V, Berk C

Turkish Journal of Neurosurgery 1996, 9:3 (Turkish)

 

10- Shunts for the treatment of hydrocephalus.

Selçuki M, Dinçer C, Ünlü A, Berk C

Turkish Journal of Neurosurgery 1996, 9:89 (Turkish)

 

11- Combined surgical treatment for lumbar disc herniation and

spondylolysthesis.

Çaglar S, Berk C, Arasil E, Erdemir B, Çetin I

Turkish Journal of Neurosurgery 1996, 9:337 (Turkish)

 

12- Surgical management of craniofacial pain.

Kanpolat Y, Savas A, Berk C

Streotact Funct Neurosurg 1996-1997, 67:56-57

 

13- Pre-operative neuroradiological evaluation in lumbar disc disease.

Berk C, Colpan E, Caglar S, Erdogan E

Turkish Journal of Neurosurgery 1997, 10:1 (Turkish)

 

14- Anterior cervical stabilization with the Spine-tech cervi-lock system.

Çaglar S, Berk C, Batay F, Asir A, Erdogan A, Arasil E

Turkish Journal of Neurosurgery 1997, 10:50 (Turkish)

 

15- MRI findings in the acute phase after cervical trauma.

Çiftçi E, Erden I, Kosucu P, Akyar S, Berk C, Arasil E

Turkish Journal of Diagnostic and Interventional Radiology 1997, 3:109 (Turkish)

 

16- The assesment of cerebrovascular reactivitiy with brain perfusion SPECT for patients with aneurysmal subarachnoid hemorrhage (abstract).

Berk F, Berk C, Egemen N, Aras G, Akin A

The American Association of Neurological Surgeons Scientific Programme 1997, 21p

 

17- Single day protocol for the evaluation of cerebral perfusion reserve with Tc-99m ECD and Acetazolamide brain SPECT in subarachnoid hemorrhage.

Berk F, Berk C, Kir KM, Egemen N, Aras G, Akin A

Turkish Journal of Nuclear Medicine 1997, 6:71 (Turkish)

 

18- Outcome prediction after subarachnoid hemorrhage with acetazolamide activated SPECT.

Berk F, Berk C, Kir KM, Egemen N, Aras G

Eur J Nucl Med 1998, 25:1061

 

19- Percutaneus selective obturator and posterior tibial radiofrequency neurotomy for the treatment of spasticity.

Kanpolat Y, Savas A, Berk C, Bademci G

Turkish Journal of Physical Theraphy and Rehabilitation 1998 1:47-50 (Turkish)

 

20- Anterior cervical stabilization with the spine-tech system.

Caglar S, Attar A, Berk C, Colpan E, Egemen N

Journal of Ankara Medical School 1998, 2:37-40 (Turkish)

 

21- New radiological definitions for the pre-operative evaluation in lumbar disc disease.

Berk C, Colpan E, Bademci G, Erdogan A

Journal of Ankara Medical School 1998, 2:95-99 (Turkish)

 

22- MR imaging in primary intraspinal extradural hydatid disease: case report.

Berk C, Çiftçi E, Erdogan A

Neuroradiology 1998, 40:390-392

 

23- Stereotactically-guided craniotomy for a cavernous hemangioma: Techical note.

Savas A, Egemen N, Berk C

Turkish Neurosurg 1998, 8:110-113 

 

24- Radiofrequency rhizotomy in the management of patients with trigeminal neuralgia due to multiple sclerosis. 

Kanpolat Y, Savas A, Berk C

Acta Neurochir (Wien) 1998, 140:852

 

25- A new method for reconstruction of cranial bony defects: Technical note with illustrative case.

Berk C, Bademci G, Arasil E

Journal of Ankara Medical School 1999, 21:113-115

 

26- The repair of large myelomeningocele defects with bipedicled fasciocutaneous flaps.

Erçöçen AR, Can Z, Berk C, Özgencil E, Yormuk E

Journal of Cumhuriyet University School of Medicine 1999, 21:93-99 

 

27- Abducens nerve palsy after radiofequency rhizolysis for trigeminal neuralgia: case report.

Kanpolat Y, Berk C, Savas A

Neurosurgery 1999, 44:1364

 

28- Tuberculosis of the skull in a patient on maintainance haemodialysis.

Nergizoglu G, Duman N, Erturk S, Keven K, Ates K, Akar H, Bademci G, Berk C, Erekul S, Erbay B, Karatan O, Ertug E.

Nephrol Dial Transplant 1999, 14(8):2019-2021

 

29- Percutaneous controlled radiofrequency rhizotomy in the management of patients with trigeminal neuralgia due to multiple sclerosis.

Kanpolat Y, Berk C, Savas A, Bekar A

Acta Neurochir (Wien) 2000, 142:685-690

 

30- Hydatid disease.

Berk C, Ciftci E

J Neurosurg Spine 2000, 93:181-182

 

31- Microsurgical anatomy and variations of the recurrent laryngeal nerve.

Berk C, Young PH

Proceedings of the Turkish Congress of Neurosurgery 2000, p192-193 (Turkish)

 

32- A calcifying fibroma of the meninges: Report of a case and review of the literature.

Ceyhan K, Berk C, Caglar S, Surucu S

Pathol Res Pract 2000, 196: 747-752

 

33- The use of high density polyethylene implants for craniectomy repair in posterior fossa surgery.

Berk C, Savas A, Kanpolat Y

Journal of Neurological Sciences (On-line, www.med.ege.edu.tr/norolbil) 2000, 17(3): #35

 

34- Bilateral trigeminal neuralgia: a therapeutic dilemma.

Berk C

Br J Neurosurg 2001, 15: 198-198

 

35- Tuberculosis and the skull.

Berk C

J Neurosurg 2001, 94: 146-147

 

36- Microvascular decompression for trigeminal neuralgia in patients over 65 years of age.

Berk C, Honey CR

Br J Neurosurg 2001, 15: 76-76

 

37- Percutaneous controlled radiofrequency trigeminal rhizotomy for the treatment of idiopathic trigeminal neuralgia: 25-year experience with 1600 patients.

Kanpolat Y, Savas A, Bekar A, Berk C

Neurosurgery 2001, 48: 524-534

 

38- A review of current surgical options for the treatment of Parkinson’s disease with special emphasis on deep brain stimulation.

Berk C

Turkish Neurosurg 2001, 11: 1-8

 

39- Deep brain stimulation for movement disorders. A brief review.

Berk C

Journal of Neurological Sciences (On-line, www.med.ege.edu.tr/norolbil) 2001, 18(2): #26

 

40- Essential tremor: A common movement disorder and emerging new alternatives in surgical treatment.

Berk C

Journal of Neurological Sciences (On-line, www.med.ege.edu.tr/norolbil) 2001, 18(3): #35

 

41- Multidimensional outcome following dominant thalamotomy in patients with Parkinson’s disease and essential tremor.

Martzke JS, Sinden M, Carr JAR, Honey CR, Berk C

Mov Disord 2001, 16 (Suppl 1): S39-S40

 

42- Neuropsychiatrical outcome from posteroventral pallidotomy: A waitlist control group study.

Carr JAR, Sinden M, Honey CR, Berk C, Martzke JS

Mov Disord 2001, 16 (Suppl 1): S21-S22

 

43- The treatment of tremor after severe head injury using thalamic deep brain stimulation.

Berk C, Honey CR

Abstract book, CNS 51st Annual Meeting, San Diego, CA, 2001, #332

 

44- The microsurgical anatomy of the recurrent laryngeal nerve.

Berk C, Honey CR

Abstract book, CNS 51st Annual Meeting, San Diego, CA, 2001, #539

 

45- Failed deep brain stimulation: a case report with postmortem correlation.

Mackenzie IR, Berk C, Honey CR

Parkinsonism and Related Disorders 2001, 7 (Suppl 1): S81-S82

Abstract book, XIV International Congress on Parkinson’s Disease, Helsinki, Finland, 2001

 

46- Microelectrode recording for pallidotomy: mandatory,beneficial or dangerous? 

Honey CR, Berk C, Palur RS, Schulzer M

Stereotact Funct Neurosurg 2001, 77(1-4): 98-100

 

47- Bilateral thalamic deep brain stimulation for the treatment of head tremor: Report of two cases.

Berk C, Honey CR

J Neurosurg 2002, 96: 615-618

 

48- A metaanalysis comparing the results of pallidotomy performed using microelectrode recording or macroelectrode stimulation.

Palur RS, Berk C, Schultzer M, Honey CR

J Neurosurg 2002, 96: 1058-1062

 

49- Percutaneous biopsy through foramen ovale: Case report.

Berk C, Honey CR

Stereotact Funct Neurosurg 2002, 78(1): 49-52 

 

50- Thalamic deep brain stimulation for the treatment of tremor due to multiple sclerosis: a prospective study of tremor and quality of life.

Berk C, Carr J, Sinden M, Martzke J, Honey CR

J Neurosurg 2002, 97(4): 815-820

 

51- Thalamic deep brain stimulation for multiple sclerosis tremor: A prospective study of tremor and quality of life.

Honey CR, Berk C, Carr J, Sinden M, Martzke J

Can J Neurol Sci 2002, 29 (Suppl.1): S20

Abstract Book, 37th meeting of the Canadian Congress of Neurological Sciences

 

52- The treatment of trigeminal neuralgia in patients with multiple sclerosis utilizing percutaneous rhizotomy: a clinical study in the British Columbian population. 

Berk C, Honey CR

Can J Neurol Sci 2002, 29 (Suppl.1): S72 

Abstract Book, 37th meeting of the Canadian Congress of Neurological Sciences

 

53- Resolution of cerebral vasospasm with trapidil; an animal model.

Bagdatoglu C, Guleryuz A, Unlu A, Kanik A, Berk C, Ozdemir C, Koksel T, Egemen N

J Clin Neurosci 2002, 9: 429-432 

 

54- Metaanalysis, pallidotomy, and microelectrodes.

Palur RS, Berk C, Schulzer M, Honey C

J Neurosurg 2002, 97: 1253-1256

 

55- Regulation of aquaporin-4 in a traumatic brain injury model in rats.

Sun MC, Honey CR, Berk C, Wong NLM, Tsui JKC 

J Neurosurg 2003, 98: 565-569

 

56- Reducing hardware related complications of deep brain stimulation.

Constantoyannis C, Honey C, Berk C, Brownstone R, Mendez I

Can J Neurol Sci 2003, 30 (Suppl.2): S61 

Abstract Book, 38th meeting of the Canadian Congress of Neurological Sciences

 

57- Unusual indications for spinal cord stimulation.

Berk C, Beauprie I, Brownstone R

Can J Neurol Sci 2003, 30 (Suppl.2): S58 

Abstract Book, 38th meeting of the Canadian Congress of Neurological Sciences

 

58- The treatment of trigeminal neuralgia in patients with multiple sclerosis using percutaneous radiofrequency rhizotomy.

Berk C, Constantoyannis C, Honey CR

Can J Neurol Sci 2003, 30(4): 220-223  

 

59- Neuroepithelial cysts presenting with movement disorders: Two cases.

Heran NS, Berk C, Constantoyannis C, Honey CR

Can J Neurol Sci 2003, 30(4): 393-396

 

60- Intracranial tuberculoma in an immunocompetent patient.

Berk C 

Acta Neurochir (Wien) 2004, 146:89

 

61- Cholesterol granulomas of the petrous apex.

Berk C 

Acta Neurochir (Wien) 2004, 146:89 

 

62- Assessing tremor reduction and quality of life following thalamic deep brain stimulation for the treatment of tremor due to multiple sclerosis: Letter to the editor.

Berk C, Carr J, Sinden M, Matrzke J, Honey C

J Neurol Neurosurg Psychiatry, 2004, 75(8): 1210-1211

 

63- Delineation of lateral tentorial sinus with contrast-enhanced MR imaging and its surgical implications.

Midia Z, Midia M, Rohrer SE, Hoeffner EG, Vandorpe R, Berk C, Midia M.

AJNR, 2004, 25(7): 1181-1188

 

64- Bilateral reversible deafness after surgery for unilateral epidermoid tumor: an unusual complication: case report.

Colpan ME, Sekerci Z, Berk C.

Neurosurgery. 2005 Apr;56(4):E870; discussion E870.

 

 

65- Brain stem injury after radiofrequency trigeminal rhizotomy: Brief report of a special case.

Berk C, Honey CR 

Acta Neurochir (Wien), 2004, 146(6): 635-636

 

 

66- Reducing hardware-related complications of deep brain stimulation.  

Constantoyannis C, Berk C,  Honey CR, Mendez I, Brownstone R

Can J Neurol Sci, 2005 May;32(2):194-200. 

 

67- Factors influencing outcome in intracerebral hematoma: a simple, reliable, and accurate method to grade intracerebral hemorrhage.

Shaya M, Dubey A, Berk C, Gonzales-Toledo E, Zhang J, Caldito G, Nanda A

Surg Neurol, 2005, 63(4): 343-348

 

68- Surgical management of intracranial cavernous malformations: the Louisiana State University Health Sciences Center, Shreveport experience.

Berk C, Shaya M, Acharya R, Nanda A. 

Southern Med  J, 2005, 98(6): 611-615

 

69- Assessment of pain control, quality of life, and predictors of success after gamma knife surgery for the treatment of trigeminal neuralgia

Jawahar A, Wadhwa R, Berk C, Caldito G, DeLaune A, Ampil F, Willis B, Smith D, Nanda A

Neurosurg Focus. 2005 May 15;18(5):E8.

 

70- Safety of anterior commissure-posterior commissure-besed target calculation of the subthalamic nucleus in functional stereotactic procedures

Acar F, Miller JP, Berk MC, Anderson G, Burchiel KJ.

Stereotact Funct Neurosurg. 2007;85(6):287-91. Epub 2007 Aug 17.

 

71- A randomized comparison of thalamic stimulation and lesion on self-paced finger movement in essential tremor

Anderson VC, Burchiel KJ, Hart MJ, Berk C, Lou JS.

Neurosci Lett. 2009 Sep 22;462(2):166-70. Epub 2009 Jul 8.

 

72- Precision and accuracy of stereotactic targeting in patients undergoing repeat sterotactic surgery

Zacest A, Berk C, Burchiel KJ.

Stereotact Funct Neurosurg. 2009;87(3):168-73. Epub 2009 May 6.

 

73- Sensitivity of high-resolution three-dimensional spoiled-gradient recalled imaging in the prediction of neurovascular compression in patients with hemifacial spasm

Raslan AM, DeJesus R, Berk C, Zacest A, Anderson JC, Burchiel KJ.

J Neurosurg. 2009 Oct;111(4):733-6.

 

74- Thalamotomy as a Treatment Option for Tremor after Ineffective Deep Brain Stimulation.

Bahgat D, Magill ST, Berk C, McCartney S, Burchiel KJ.

Stereotact Funct Neurosurg. 2012 Nov 13;91(1):18-23.

Areas of Interest

What Is the Structure of the Human Brain? How Does the Human Brain Work?

The human brain is part of the central nervous system and has a complex structure. In adults, it weighs approximately 1.4 kg and consists of blood vessels, neurons, and supporting glial cells. From the early stages of life to adulthood, the weight and structure of the brain continuously change and develop. Both genetic and environmental factors can directly or indirectly affect brain development.

What is a Cervical Herniation? Causes, Symptoms, and Treatment

Cervical herniation occurs when one of the discs in the cervical spine (neck vertebrae) protrudes or leaks a gel-like substance outside of the disc. This usually happens when the inner part of the disc pushes outward through the outer part. Cervical herniation can lead to various types of pain in individuals' bodies. However, some patients may not experience any pain. In addition to pain symptoms, numbness or weakness in the arm and hand may also occur. Cervical herniation can result from muscle weakness, trauma, or neck injuries. Treatment methods include rest, exercise, physical therapy, and pain-relief medications. However, in more severe cases, surgical intervention may be necessary.

Essential Tremor: Symptoms and Treatment

Essential tremor, commonly known as shaking disorder, is a condition characterized by tremors in the hands, arms, or other parts of the body. The frequency of this condition increases with age and is more common between the ages of 10-19 or 50-59. Essential tremor affects approximately 1% of the global population, with an estimated 5% of people over the age of 60 affected. While it is not a dangerous disease, if left untreated, it can interfere with daily activities. There are several treatment options, which can be chosen based on the individual's condition and the severity of the disease. Essential tremor is a slowly progressive condition, which means it may take many years to reach a stage where it significantly impacts one’s quality of life.

What is Parkinson's Surgery?

What is Deep Brain Stimulation? Surgery and Effects of DBS

Deep Brain Stimulation (DBS), commonly referred to as "brain pacemaker" surgery, is a surgical intervention used in the treatment of neurological disorders. This procedure involves placing electrodes within specific areas of the brain and connecting them to a battery-operated device. DBS is recognized as an effective option for managing symptoms of various neurological disorders, particularly Parkinson's disease.

Spinal Tumor: What It Is, Causes, Symptoms, and Treatment

Tumors form as a result of uncontrolled reproduction and growth of certain cells in any tissue or organ of the body.

What is Spine Surgery?

The spine is a bridge made up of bones, joints, and discs that extend between the head and the coccyx, carrying a large portion of the body’s mass.

Hydrocephalus: What It Is, Causes, Symptoms, Diagnosis, and Treatment

Hydrocephalus is a condition that can occur at any age, including during fetal development.

What is Cerebellar Herniation, and What Are the Diagnosis and Treatment Options?

Although the exact cause of cerebellar herniation occurring at any age is not fully understood, significant progress has been made in its treatment.

What is Neurosurgery (Neurochirurgery)? Neurosurgical Diseases

Neurosurgery, also known as brain and nerve surgery, is the branch of medicine that deals with diseases of the brain and nervous system.

What is a Brain Tumor?

A brain tumor is a condition that occurs when the cells in the brain’s own tissue undergo uncontrolled growth or when cancer cells from another part of the body reach the brain through the bloodstream and spread to this area.

Symptoms and Treatment Methods of Brain Tumors

Brain tumors are divided into two groups: benign (non-cancerous) and malignant (cancerous).

Brainstem Tumor Symptoms, Diagnosis, and Treatment Methods

The brainstem anatomically connects the brain to the spinal cord.

Brain Cancer: What It Is, Symptoms, Diagnosis, and Treatment

Brain cancer is the rapid and uncontrolled multiplication and growth of malignant tumor cells in the brain. The cells responsible for brain cancer have the ability to self-renew. Brain tumors can occur in the pituitary and pineal glands, the membrane on the surface of the brain, and the nerves. Secondary tumors, which originate in other parts of the body and spread to affect the brain, are more common than primary brain tumors that arise directly in the brain. The most commonly observed cases of brain cancer originate from secondary brain tumors. In 2022, it was reported that more than 1,900 people, with an average age of 59, were diagnosed with brain cancer worldwide.